Abstract

ARGUELLO-RANGEL, Jeraldyn; TRIANA-GARCIA, Pedro A  and  ESLAVA-MOCHA, Pedro R. Eosinophlic granular cells/Mast cells and their relation with the effects of herbicides: Case of glyphosate and accompaning surfactants on fish. Orinoquia [online]. 2015, vol.19, n.1, pp.59-76. ISSN 0121-3709.

The mast cells of the immune system, which in fish are referred to as eosinophilic granule cells (EGC), have been related to different types of physiological and pathological responses in fish. Recently, there is increased scientific interest related to these cells' participation in reactions to water pollution, against infectious agents, and lastly, their use as models for studying the allergic and neurodegenerative disorders in humans. Numerous studies in various species of teleost have shown that the behavior of CGE/MC are relevant for studying anti-infective mechanisms. Also, researchers have studied their response to exposure to pollutants, such as herbicides, which can interfere with the nervous and olifactory systems of fish. This review of the literature shows data from various studies on mast cells of fish which suggest the importance of them being a good biomarker to contaminants. This review emphasizes the participation in the responses of different organs and tissues from exposure to herbicides such as glyphosate and accompanying surfactants in the mixtures that are sprayed, and the morphological, physiological, and pathological role, and some possible ways to study them as well in the nervous system, especially compared to sublethal exposures to pesticides.

Keywords : Mast Cell; POEA; Roundup®; toxicity; toxicological fish pathology; immunohistochemistry; telencephalon.

        · abstract in Spanish | Portuguese     · text in Spanish     · Spanish ( pdf )