Abstract

VASQUEZ-ARTEAGA, Marcial et al. DOSIMETRY OF RADIOPHARMACEUTICALS USED IN ADULT PATIENTS WITH SUSPECTED PULMONARY EMBOLISM. Momento [online]. 2021, n.63, pp.22-33.  Epub Aug 27, 2021. ISSN 0121-4470.  https://doi.org/10.15446/mo.n63.95617.

The absorbed dose of radiopharmaceuticals is estimated in adults with suspected pulmonary embolism explored by ventilation/perfusion studies. For pulmonary ventilation studies 81mKr, 133Xe, 99mTc (Technegas)-aerosol and 99mTc (DTPA)-aerosol are used. For perfusion agents, 99m Tc(MAA), 99mTc (MSA) (macroaggregates and albumin microspheres) are used. For the dose calculation, the MIRD methodology and the anthropomorphic representation of the biokinetic organs of Cristy-Eckerman are used. In ventilation/perfusion studies, the lowest dose absorbed by the lungs with suspected embolism is due to 81mKr/99mTc (MSA), and the highest dose is due to 99mTc (Technegas)/99mTc (MAA) calculated for activities of 150 MBq for perfusion agents and 40 MBq for ventilation agents.

Keywords : Internal dosimetry; radiopharmaceuticals; ventilation; pulmonary embolism.

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