Objective:

To investigate the pharmacological adherence and the knowledge of patients undergoing oral anticoagulation therapy with outpatients follow-up.

Method:

Cross-sectional study with quantitative approach.

Results:

222 patients were evaluated, of which 60.8 % were classified as non-adherents and 63.1 % had inadequate knowledge regarding oral anticoagulant. Non-adherence was related to longer treatment time (p <0.001) and to patients with inr values outside the therapeutic range (p = 0.022). Inadequate knowledge was associated with low educational level (p < 0.001), sedentary lifestyle (p = 0.027), shorter outpatient follow-up (p < 0.001), and patients with inr values outside the therapeutic range (p = 0.012).

Conclusion:

In view of the results, it is evident the need for health education strategies that address this public, considering individual understanding and pharmacological adherence as crucial in therapy.

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