Abstract

BAUTISTA M., WILSON A.; PARRA C., SANDRA L.; BASTIDAS G., ALIRIO R.  and  OLIVEROS, HENRY. CLINICAL AND PARACLINICAL ASSOCIATED FACTORS RELATED TO THE ADMISSION OF PATIENTS WITH A DIAGNOSIS OF MALARIA TO THE INTENSIVE CARE UNIT OF THE HOSPITAL MILITAR CENTRAL. rev.fac.med [online]. 2008, vol.16, n.2, pp.184-191. ISSN 0121-5256.

An analytic observational study of retrospective cohorts was carried out during the period comprised between January first 2002 and January 31, 2008 to determine the clinical and paraclinical factors associated with the patients admitted to the Intensive Care Unit (ICU) of the Hospital Militar Central with the diagnosis of malaria. The sample size was calculated using the program TAMAMU ® and 298 clinical histories were selected of which 278 fulfilled the inclusion criteria. Of the 278 patients, only 7.91% were admitted to ICU. Variables associated with admission to ICU were dyspnea (P <0.001), parasitemia greater than 50.000/µL (P = 0.001), use of antibiotics (P=0.001), platelet count of <83.000/mm3 (P = 0.01), and use of antimalarics in the first eight hours of admission to the hospital (P = 0.001). In conclusion, the presence of dyspnea, trombocytopaenia, parasitemia greater than 50.000/µL were related with the admission to ICU in patients with the diagnosis of malaria, use of antimalarics in the first eight hours of admission to the hospital is a protector factor but further clinical trials are needed in order to clarify the association with the use of use antibiotics.

Keywords : malaria; parasitemia; thrombocytopaenia.

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