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Revista Med

Print version ISSN 0121-5256

Abstract

RODRIGUEZ P., YOVANY  and  GODOY, JAVIER I.. GERM CELL TUMOUR. rev.fac.med [online]. 2008, vol.16, n.2, pp.200-214. ISSN 0121-5256.

Germ Cell Tumours are malignancies derived from primordial germ cells. They are classified as seminomatous and non seminomatous, the latter divided based on the cellular differentiation as Embrionary germ cell, Choriocarcinomas, Yolk salk tumors and mature and inmature teratoma. They are the most frequent tumors in men between the ages of 20 and 35 and correspond to 90% of testicular tumors found as non-symptomatic hard painless testicular masses. Their embryologic origin as well as their migration from the primordial gut toward the seminiferous tubules explains the emergence of GCT in the mediastinum and retroperitoneum. In this review there is a description about embryologic, clinical and pathologic characteristics of the disease, as well as staging and treatment.

Keywords : neoplasms germ cell and embryonal; carcinoma embryonal; choriocarcinoma; teratoma; testicular neoplasms.

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