Abstract

FERNANDEZ A., DANIEL G; MANCIPE G., LILIANA C.  and  FERNANDEZ A., DIANA C.. ORGANOPHOSPHORUS POISONING. rev.fac.med [online]. 2010, vol.18, n.1, pp.84-92. ISSN 0121-5256.

Organophosphorus compounds are a group of organic substances derived from the chemical structure of phosphorus. They have a large number of applications and utilities. They are used as oil additives, solvents, in the industry of dyes, varnishes, artificial leather, electrical insulation, waterproofing, plastic softeners, fungicides and others. Given its wide distribution and use in different industries and trades, organophosphorus compounds can be taken accidentally causing intoxication and can be used with the intention to commit suicide. The intoxication with organophosphorus compounds produces a characteristic clinical syndrome with cholinergic symptoms after stimulation of acetylcholine receptors. The medical management of these patients could make the difference between life and death, hence the physician and all health personnel in the emergency department should be able to recognize and manage poisoning symptomatology properly.

Keywords : organophosphorus; intoxication; acetylcholine; acetylcholinesterase.

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