Abstract

TIBADUIZA MOGOLLON, YURIET ALEXANDRA; MIRANDA-DIAZ, AUDREY JOSÉ  and  NAVAS TORREJANO, DIANA STEFANIA. LESER-TRÉLAT SIGN: PARANEOPLASTIC SIGN IN METASTATIC BREAST CANCER, CASE PRESENTATION. Rev. Med [online]. 2018, vol.26, n.2, pp.60-64.  Epub Dec 01, 2018. ISSN 0121-5256.

The Leser-Trelat sign is a sudden and rapid growth eruption of large seborrheic keratoses secondary to an internal neoplasm. These may be related to pruritus and acanthosis nigricans. The neoplasms frequently associated with the Leser-Trélat sign are gastric, colon and breast adenocarcinomas, represented to a lesser extent by lymphomas, squamous cell carcinoma and hematological malignancies. As the Leser-Trélat sign is an uncommon paraneoplastic dermatosis, a case of a 76-year-old patient with advanced breast cancer associated with this sign is presented.

Keywords : eruption; seborrheic keratosis; pruritus; acanthosis nigricans; adenocarcinoma, breast neoplasms.

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