Abstract

GONZALEZ, LuisAlonso  and  RAMIREZ GOMEZ, Luis Alberto. Late-onset systemic lupus erythemathosus. Rev.Colomb.Reumatol. [online]. 2008, vol.15, n.3, pp.168-185. ISSN 0121-8123.

Late-onset lupus has been defined in different studies as onset of lupus after age 50 and constitutes 6-18% of the lupus population. According to literature the most common clinical features are interstitial lung disease, serositis and Sjögren´s syndrome. An insidious onset, low prevalence, non-specific manifestations at the beginning of the disease and similarity to other common disorders may delay its diagnosis. Although disease activity tends o be lower in these patients, they tend to accrue more damage and experience higher mortality than patients with early-onset lupus. Thus, late-onset SLE should not be considered as a benign disease.

Keywords : age; systemic lupus erythematosus; late onset.

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