Abstract

MARTINEZ CORDERO, Humberto et al. History of glucocorticoids. Rev.Colomb.Reumatol. [online]. 2010, vol.17, n.3, pp.147-171. ISSN 0121-8123.

In this paper we do a complete review of the history of steroids from Thomas Addison, who described the characteristics of the disease that bears his name, through Edward Kendall who was the first to synthesize the compound E or cortisone, Philipe Hench and his group who made the clinical application of glucocorticoids in a patient with rheumatoid arthritis, up to Hermann Meyer with current concept on circadian rhytms. It is a fascinating story that lets us know in detail all the steps that led to the discovery of steroids and its clinical application in various diseases such as rheumatoid arthritis and systemic lupus erythematosus.

Keywords : history; glucocorticoids; mineralocorticoids; rheumatoid arthritis; systemic lupus erythematosus.

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