Abstract

BOLIVAR GIRALDO, Isabel et al. Cutaneous ulcers and thrombotic neuropathy as first manifestations in a patient with antiphospholipid syndrome. Rev.Colomb.Reumatol. [online]. 2010, vol.17, n.3, pp.186-190. ISSN 0121-8123.

This following case report describes a 34 years-old man with chronic clinical skin ulcers and left lower monoparesis. Electromyography revealed sensory neuropathy of the left superficial fibular nerve; the ecographic studies showed absence of artery or venous disorder. The patient showed no improvement of skin lesions with aggressive immunosuppression. The biopsy of the skin and the sural nerve reported thrombi and absence of inflammatory infiltrates; findings that support the diagnosis of thrombotic vasculopathy and neuropathy. The presence of lupus anticoagulant, prolonged PTT and positive anti-B2 glycoprotein antibodies were documented.

Keywords : antiphospholipid syndrome; skin ulcers; fibular neuropathies.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )