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Revista Colombiana de Reumatología

versión impresa ISSN 0121-8123


IGLESIAS RODRIGUEZ, Antonio; GIL, Diana; RESTREPO, José Félix  y  IGLESIAS GAMARRA, Antonio. History of Devic's disease. Rev.Colomb.Reumatol. [online]. 2011, vol.18, n.4, pp.271-284. ISSN 0121-8123.

In this paper we do a complete review of Devic's disease, from its first descriptions by Eugene Devic, to the current concept, which is considered a neuromyelitis optica (NMO). We present the different forms of presentation of NMO as well as clinical and laboratory findings that distinguish this entity from multiple sclerosis, a task that frequently is not easy to perform because of the similarity in clinical presentation. Its differentiation is important because the treatment and prognosis differ between these two diseases. However the discovery of NMO IgG antibodies directed against aquaporin-4 water channels was a critical step in such differentiation. We made special mention of Devic's disease and lupus, and finally make some notes on the available treatment for this pathology.

Palabras clave : Devic'disease; systemic lupus erythematosus; neuromyelitis optica; multiple sclerosis.

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