Abstract

IGLESIAS-GAMARRA, Antonio et al. History of treatment of primary vasculitis. Rev.Colomb.Reumatol. [online]. 2012, vol.19, n.3, pp.131-157. ISSN 0121-8123.

Primary vasculitis is one of the rheumatic diseases with variable clinical expression and poor prognosis when not treated properly. In this review we analyze detailed treatment of this disease in different forms of primary vasculitis, starting with the use of corticosteroids from almost its discovery in 1949, to other immunosuppressant's such as cyclophosphamide, methotrexate, azathioprine, mycophenolate mofetil, as well as biological drugs such as rituximab and anti-TNF. Special mention is made on the guidelines of treatment for vasculitis of both large and small vessel, implemented since 2009 by the European Group Study of Vasculitis.

Keywords : Primary vasculitis; Wegener granulomatosis; Takayasu arteritis; poliarteritis nodosa; microscopic poliangeitis; giant cell arteritis.

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