Abstract

ZAPATA-CARDENAS, Andrés et al. The heart in systemic lupus erythematosus: Structured literature review. Rev.Colomb.Reumatol. [online]. 2013, vol.20, n.3, pp.148-154. ISSN 0121-8123.

Abstract Systemic lupus erythematosus is an inflammatory disorder of autoimmune origin that can involve multiple organs. Cardiac compromise can occur in patients with established disease, or it can be the initial manifestation in some of these patients. The heart commitment in this disorder can vary in their severity until producing life-threatening conditions, and it can affect any structure or heart tissue. Additionally, the systemic inflammation present is associated to accelerated atherosclerosis that can evolve to early ischemic heart disease, increasing the risk of cardiovascular illness significantly when it is compared with general population. The main characteristics of heart manifestations in systemic lupus erythematosus are discussed, as well as their diagnosis and treatment.

Keywords : Heart; Lupus erythematosus systemic; Autoimmunity; Autoantibodies; Myocarditis; Heart failure.

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