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Revista Colombiana de Reumatología

Print version ISSN 0121-8123

Abstract

VELASQUEZ FRANCO, Carlos Jaime et al. Estimated quality of life and health related utility measurements in a population of Colombian patients with systemic lupus erythematosus. Rev.Colomb.Reumatol. [online]. 2013, vol.20, n.4, pp.183-194. ISSN 0121-8123.

Abstract Background: The possibility of irreversible organ damage secondary to systemic lupus erythematosus activity or treatment, inevitably affects the health-related quality of life of these patients. This is a concept which is affected by social, cultural and familial factors, and is a primary outcome in the prognosis of chronic diseases. Objective: To determine the health-related quality of life and utility values in a sample of patients with a diagnosis of systemic lupus erythematosus, and its correlation with activity and chronicity. Materials and methods: Observational, descriptive, cross-sectional study in subjects with systemic lupus erythematosus according to 1997 ACR criteria. Outcomes: Evaluation of health-related quality of life using the SF-36 questionnaire; values of utility, social and psychological parameters related to the impact of the disease with HAD scale, the Duke UNK questionnaire, and its association with lupus activity with SELENA/SLEDAI, and organic damage through the SLICC/ACR. Results: A total of 152 patients were included, of whom 90.1% were women.The mean values of the health-related quality of life domains ranged from 52.9 in the physical performance to 67.3 in the social function. As regards the evaluated associations, these were weak, but statistically significant, except for the DUKE-UNK variable. Conclusions: The majority of patients with systemic lupus erythematosus had a healthrelated quality of life located above the 50th percentile.The most compromised dimensions were those related to physical health.

Keywords : Lupus erythematosus systemic; Quality of life, Sickness impact profile; Health status indicators; Chronic disease.

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