Abstract

DIAZ CORONADO, Juan Camilo et al. Clinical manifestations of Monckeberg's sclerosis. Report of case and literature review. Rev.Colomb.Reumatol. [online]. 2017, vol.24, n.2, pp.118-122. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2016.12.004.

Monckeberg's sclerosis is a rare and low prevalence disease of unknown cause in which small and medium size arteries suffer calcification of the middle layer, leading to a reduction in calibre.

Clinically, the disease manifests by the appearance of arterial type ulcers on the skin of upper and lower extremities. Its diagnosis is difficult, and requires histopathological studies.

Some rheumatic conditions, such as polyarteritis nodosa and giant cell arteritis may mimic this process. Treatment of the disease is not well established. Although the use of calcium chelators such as sodium thiosulfate has been proposed, the few available studies have failed to show significant results.

Keywords : Monckeberg's sclerosis; Necrotic ulcers.

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