Abstract

DE LA CAMARA FERNANDEZ, Isabel; MOLINA-LARIOS, Rina Aicxa  and  JOVEN-IBANEZ, Beatriz. Cogan's syndrome: A case report with partial response to tocilizumab and a literature review. Rev.Colomb.Reumatol. [online]. 2018, vol.25, n.4, pp.298-300. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2017.09.001.

Cogan’s syndrome is a chronic inflammatory disease typified by interstitial keratitis and Meniere-like auditory involvement, and it can be accompanied by systemic vasculitis. It’s a rare disease and its diagnosis is difficult and often late, which increases the risk of sequelae, such as visual loss or deafness. In addition, its treatment is not well-established and is based on case reports that have observed efficacy of drugs such as cyclophosphamide, anti-TNF or tocilizumab. A case of Cogan's syndrome is presented that did not respond to methotrexate, cyclophosphamide, or anti-TNF, but with a partial response to tocilizumab.

Keywords : Cogan's syndrome; Vasculitis; Tocilizumab.

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