Abstract

HERRERA, Cristina N.; BARRENO V., Martha E.; QUINTANA VEGA, Verónica J.  and  SUQUILANDA FERIA, Danny B.. Hypoacusis and cutaneous vasculitis as first clinical manifestation of granulomatosis with polyangiitis in a 14 year-old girl. Rev.Colomb.Reumatol. [online]. 2019, vol.26, n.3, pp.216-219.  Epub Aug 20, 2020. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2018.09.002.

Granulomatosis with polyangiitis is a small- and medium-sized vasculitis. It is characterised by formation of granulomas and necrotising inflammation with a predilection for the respiratory tract and glomeruli. The case is presented of a 14-year-old female debuting with hypoacusis, skin lesions, sinusitis; episcleritis, anti-PR3 ANCA positivity and histological findings from the skin lesions with neutrophilic infiltration, necrosis and fibrin. Granulomatosis with polyangiitis can present otological and skin manifestations as initial signs, and it is important to take the differential diagnosis into consideration.

Keywords : Granulomatosis with polyangiitis; Children; Vasculitis; Anti-cytoplasmic neutrophil antibodies; Hypoacusis.

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