Abstract

OSPINA CAICEDO, Ana Isabel et al. Sporadic Paget's disease of the bone. Case series and literature review. Rev.Colomb.Reumatol. [online]. 2020, vol.27, n.2, pp.103-111.  Epub Apr 22, 2021. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2019.07.004.

Paget's disease of the bone is a metabolic bone disease of unknown origin, and is characterised by an increased phase of resorption, followed by an aberrant osteoformation phase. It is common in Europe, North America, New Zealand, and Australia, but infrequent in Asia, the Middle East, Africa, and in the Colombian population there are case reports. It is usually asymptomatic and is diagnosed incidentally by radiographic findings or an elevated alkaline phosphatase. The use of bisphosphonates favours the control of bone turnover and prevents complications such as fractures. A series of cases in Colombia is presented, along with a review of the literature.

Keywords : Osteitis deformans; Paget's disease of bone.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )