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Revista Colombiana de Reumatología

Print version ISSN 0121-8123

Abstract

MOLINA-RIOS, Sebastian; ORDONEZ C., Eliana  and  QUINTANA-LOPEZ, Gerardo. Osteoarticular manifestations of systemic sclerosis: a systematic review of the literature. Rev.Colomb.Reumatol. [online]. 2020, vol.27, suppl.1, pp.85-110.  Epub Aug 22, 2021. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2019.11.006.

Introduction:

Osteoarticular manifestations (OAM) are frequently present in patients with systemic sclerosis (SSc). These OAM are related to important functional disability and a severe impact on patient's life quality, therefore, they require special attention from clinicians.

Objective:

Determining the frequency of reported OAM in SSc patients, the general impact of osteoarticular manifestations in patient's condition and the tools available for diagnosis and treatment.

Methodology:

A systematic review of the literature was performed for information published between January 1970 and December 2018 in the medical research databases of: Medline, Embase, Lilacs, Scielo, Cochrane and clinicaltrials.gov.

Results and Conclusions:

A total of 116 articles were included in this review. The type and prevalence of the different OAM reported in the literature were determined. In addition to the evolution of their diagnostic methods, there are more validated methods to assess the impact of OAM in patients with SSc. Randomized clinical trials are required to establish the best treatment strategy for these patients.

Keywords : Scleroderma; Systemic; Joints; Bone and Bones/complications; Quality of life; Systematic review.

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