Abstract

REYES JARABA, Carlos Andrés et al. Sjögren's syndrome: Epidemiology and clinical manifestations. Rev.Colomb.Reumatol. [online]. 2022, vol.29, n.4, pp.310-324.  Epub Aug 14, 2023. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.12.007.

Sjögren's syndrome is an entity of rheumatic origin, with complex autoimmune characteristics, in which the salivary and lacrimal glands are mainly compromised. It has two forms of presentation, one primary and the other secondary, and in both forms there is evidence of exocrine glands involvement. The clinical spectrum of Sjögren's syndrome is very heterogeneous and is classified into glandular and extra-glandular manifestations, but not mutually exclusive. It is recommended that all patients with parotid inflammation, purpura, hypergammaglobulinaemia, anti-SSa, and anti-SSb should be seen to have a greater risk of presenting with a severe systemic presentation, and it is recommended to carry out a more strict medical control. Population studies that have attempted to describe the incidence and prevalence of Sjögren's syndrome in various countries throughout the world are to some extent discordant between one registry and another. Although Sjögren's syndrome is more common in women, ocular involvement predominates in men, and it can occur in all ages, mainly between the third and fifth decades of life. In children it is rare. It is also considered as a common connective tissue disease, where the data on the global incidence rate and prevalence are underestimated.

Keywords : Sjögren's syndrome; Xerostomia; Epidemiology; Signs and symptoms.

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