Abstract

TOBAR-MARCILLO, Marco; TAPIA-RANGEL, Édgar  and  PABLO, Víctor Rosales-Don. Takayasu arteritis associated with focal and segmentary glomerulosclerosis. Rev.Colomb.Reumatol. [online]. 2022, vol.29, n.4, pp.401-405.  Epub Aug 18, 2023. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2021.03.006.

Takayasu arteritis (TA) is a large vessel vasculitis that affects young people, related to cardiovascular outcomes and chronic kidney disease. We present the case of a 20-year-old male with a diagnosis of TA, who developed chronic kidney disease, impaired renal blood flow was ruled out, renal biopsy was compatible with focal and segmental glomerulosclerosis of a collapsing variety, other possible aetiologies were excluded. The mechanisms that mediate this association have not been determined, immune-mediated mechanisms are proposed. According to our review, this is the second reported case of this association and the first with a collapsing variety.

Keywords : Takayasu arteritis; Focal segmental glomerulosclerosis; Nephritic syndrome; Renovascular hypertension; Blood flow; renal.

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