Abstract

TAMAYO CARBON, Alicia María et al. Effects of lipografts in immune-driven lipoatrophies. Case studies. Rev.Colomb.Reumatol. [online]. 2022, vol.29, n.4, pp.423-428.  Epub Aug 22, 2023. ISSN 0121-8123.  https://doi.org/10.1016/j.rcreu.2020.10.004.

Lipodystrophy is a pathological condition associated with an abnormal body adipose tissue redistribution. Facial lipoatrophy can be a consequence of congenital, acquired, or involutional. The lipograft is an autologous fat transplant, which constitutes a treatment option that provides volume, tissue regeneration, and advantages in relation to other fillers in autoimmune diseases. The aim is to highlight the filling action and the metabolic effect of facial lipotransfer, due to the grafted adipocytes survival, and the adipose tissue derived stem cells regenerative activity obtained by nano-fat in patients with facial lipoatrophy. Lipoinjection improves the architecture of the new dermis and increases its functional capacity. It is a treatment with autologous tissue (fatty graft) with great efficacy in relation to other alloplastic filler materials capable of exacerbating an inflammatory response mediated by antibody production.

Keywords : Lipograft; Lipoatrophy; Cutaneous lupus; Scleroderma.

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