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Revista Médica de Risaralda

Print version ISSN 0122-0667


BOLIVAR-MEJIA, Adrián; CALVO-BETANCOURT, Lauren S; ROBERTO-AVILAN, Sandra  and  CONTRERAS-GARCIA, Gustavo Adolfo. Alloimmune recurrent spontaneous abortion. Revista médica Risaralda [online]. 2013, vol.19, n.1, pp.81-85. ISSN 0122-0667.

The mechanisms underlying the human reproduction are very complex, so any pregnancy loss implies the need of considering various etiologies, even more if those pregnancy losses are recurrent within which the immunity plays an important role. Since decades, the alloimmune factor has been recognized as a frequent trigger of the pregnancy interruption, thus becoming relevant its study in women with recurrent miscarriage. In the present article, through a systematic search of information, details concerning to the physiopathology, diagnosis and treatment of the recurrent miscarriage of alloimmune etiology are reviewed, looking to sensitize the health professional about its consideration when evaluating a woman with recurrent pregnancy loss.

Keywords : habitual abortion; HLA antigens; lymphocyte transfusion; recurrent miscarriage.

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