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Revista Médica de Risaralda

Print version ISSN 0122-0667

Abstract

ALZATE, John Alexander et al. Optic neuritis in the presence of antiphospholipid antibodies of syphilitic origin: a forgotten diagnosis. Revista médica Risaralda [online]. 2018, vol.24, n.1, pp.64-69. ISSN 0122-0667.

Abstract :optic neuritis is uncommon as an ocular syphilis clinical presentation; the lack of typical features generates delay in the diagnosis. We describe the case of a 47-year-old woman, immunocompetent with a 4-month history of left visual acuity progressive of left side reduction, associated with pain, conjunctival injection and headache, physical examination with lumpy vision and fundus with signs of ocular inflammation, within the diagnostic evaluation, serum VDRL, FTA-ABS was reactive, with ANAS and IgG anticardiolipin antibodies serum positivity, lumbar punction was taken with reactive VDRL, optic neuritis by neurosyphilis was diagnosed, with antiphospholipid antibodies cross reactivity , treatment with crystalline penicillin 24 000 000 of units day for 14 days was started . In patients with signs of ocular inflammation, VDRL should be performed, confirmed with a treponemal test, and a lumbar puncture should be performed. Early treatment is associated with improvement of visual outcomes.

Keywords : syphilis; optic neuritis; neurosyphilis; ocular syphilis; antiphospholipid antibodies.

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