Abstract

LEMUS-BARRIOS, Gustavo  and  HENAO-VELASQUEZ, Carlos. Reporte de caso Nefropatía C1q. Revista médica Risaralda [online]. 2018, vol.24, n.1, pp.70-72. ISSN 0122-0667.

Abstract: C1q nephropathy is a rare glomerulonephritis characterized by diffuse, dominant or codominant mesangial deposits of C1q complement, in the absence of a clinical and immunological profile of systemic lupus erythematosus (SLE). We describe a case of a 27-year-old female with nephrotic syndrome of unclear cause, in whom SLE and antiphospholipid syndrome (SAF) were ruled out but who had a kidney biopsy compatible with this disease. Immunofluorescence showed mesangial deposits of C1q ++, IgG ++, IgM ++ C3 ++, and absence of IgA and C4 deposits. After the diagnosis, immunosuppressive management was established, achieving clinical stability. A case description and literature review of this rare cause of nephrotic syndrome is performed.

Keywords : nephropathy C1q; Nephrotic syndrome; Adult.

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