Abstract

BERMEO-ANTURY, Elías  and  QUIMBAYA, Mauricio. NEXT GENERATION SEQUENCING AND ITS EUGENICS CONTEXT IN THE HUMAN EMBRYO. pers.bioét. [online]. 2016, vol.20, n.2, pp.205-231. ISSN 0123-3122.  https://doi.org/10.5294/PEBI.2016.20.2.7.

The advent of omic technologies and, more specifically, the progress made with specific second- and third-generation sequencing technologies, gives us the possibility of knowing the particular sequence of individual genomes at a relatively affordable cost. In the not too distant future, these sequencing technologies combined with specific functional analysis will be used, at a genomic level and with a much finer degree of detail than the old molecular diagnostic tests, to identify the diseases associated with each person's genetic map. New dilemmas in different contexts have emerged with the advent of these technologies. From a bioethical perspective, the problem is not rooted in detailed research on the human genome per se, but in the purpose that can be given to information derived from this type of scientific research, which could become a useful tool for selecting, rejecting and discriminating against persons, because they have a hereditary disease or the potential to develop specific diseases in the future. This article analyzes the relationship between the eugenic mentality, the concept of quality of life, and genomic molecular diagnosis, when applied to human embryos for the purpose of preventing their implantation. Such action threatens the very life and dignity of a human being in its early stages of development.

Keywords : Omics; second- and third-generation genome sequencing; molecular diagnosis; eugenics; quality of life.

        · abstract in Spanish | Portuguese     · text in Spanish     · Spanish ( pdf )