Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Citado por Google
- Similares en SciELO
- Similares en Google
Compartir
Revista Colombiana de Biotecnología
versión impresa ISSN 0123-3475
Resumen
GOMEZ VALDERRAMA, Juliana y VILLAMIZAR, Laura. Baculovirus: Hosts and specificity. Rev. colomb. biotecnol [online]. 2013, vol.15, n.2, pp.143-155. ISSN 0123-3475. https://doi.org/10.15446/rev.colomb.biote.v15n2.41273.
Baculoviruses are insect pathogenic viruses widely used as bioinsecticides for controlling of several agricultural important pests and more recently as protein expression vectors and gene therapy vectors. One of its main characteristics is its high host-specificity including a very narrow range of insect species, which often belong to the same family. However, to understand the mechanisms involved in the definition of baculoviruses host range is necessary in order to assess the security and safety of its use and to determine the possibility of improving their properties for biotechnological applications through the construction of recombinant baculovirus with different host ranges. In the present article the main mechanisms involved in baculoviruses host range as specificity for entering into the host cells, the possibility of viral genome replication, the control of biochemical and molecular insect processes and the interactions virus-host regulating the multiplication of the infectious agent, and the prospects of applying this knowledge will be reviewed.
Palabras clave : infección viral; rango de hospederos; evolución; resistencia.