Resumo

ARIZA MARQUEZ, Yeimy Viviana; BRICENO BALCAZAR, Ignacio  e  ANCIZAR ARISTIZABAL, Fabio. Treatment of breast cancer and pharmacogenetics. Rev. colomb. biotecnol [online]. 2016, vol.18, n.1, pp.121-134. ISSN 0123-3475.  https://doi.org/10.15446/rev.colomb.biote.v18n1.57723.

Breast cancer is one of the most prevalent diseases in women with increasing mortality in several countries (GLOBOCAN 2012). The use of pharmacogenetics and pharmacogenomics in patients with breast cancer allows generating personalized health for treating each patient as an individual, as each patient has unique needs when supplying a treatment. The purpose of this review is to identify genetic variants reported in the scientific literature, where different populations are evaluated and for possible use as a tool for medical precision. Colombian population is unique and therefore population studies are needed to define the genetic profiles to be implemented.

Palavras-chave : breast cancer; pharmacokinetic; tamoxifen; hormone therapy.

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