Abstract

ARISTIZABAL, Javier Ángel et al. Sentinel Node Biopsy in Breast Cancer After Neoadjuvant Therapy in a Latin-American population. rev.colomb.cancerol. [online]. 2015, vol.19, n.1, pp.3-9. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2014.10.002.

Objective: To determine the usefulness of sentinel node biopsy in breast cancer after neoadjuvant treatment. Methods: A study of a diagnostic test. Results: The analysis was carried out on 67 Latin-American patients treated in the Instituto Nacional de Cancerología (Bogotá, Colombia), obtaining an axillary migration rate of 85%. The sentinel node identification rate was 90%. The false negative rate is 25%. The performance of the diagnostic test shows a sensitivity of 75%, specifity of 100%, positive predictive value of 100%, negative predictive value of 77.5%, and 85.6% accuracy. Conclusions: The results of our study show that this technique is not recommended as standard procedure, even in patients with clinically negative axilla confirmed by axillary ultrasound. The high percentage of false negatives may be due to the high number of patients with locally advanced disease in our series.

Keywords : Sentinel Lymph Node Biopsy; Axillary clearance; Breast Neoplasms; Neoadjuvant Therapy.

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