Objective:

To determine adherence to follow-up and outcome of lesions in women diagnosed with grade 1 cervical intraepithelial neoplasia (CIN 1).

Methodology:

The study included non-pregnant women aged 18 or older, referred for col poscopy, with a colposcopy directed biopsy diagnosis of CIN 1, with no history of prior CIN, hysterectomy or cervical ablative therapy. Participants answered a questionnaire on risk fac tors, and the outcome of previous cytology and colposcopy was documented. All women should have been followed up for 1 year with cytology and colposcopy every six months. Those who did not have cytology and colposcopy / colposcopy assessments or documented treatments after 15 months were considered as non-adherent.

Results:

A total of 40 patients with CIN 1 were included. The loss to follow-up rate of loss was 17/40 (42.5%). The demographic and clinical variables most frequently associated with non-adherence to follow-up were null parity and early initiation of sexual intercourse. The progression of low-grade to high-grade lesion was observed in 4.3%. 22.5% failed Conservative treatment failed conservative treatment and moved to invasive therapy.

Conclusion:

The rate of loss to follow-up was high, with a considerable referral from conser vative to invasive therapy. A large percentage of patients had regression of CIN 1. This study should help clarify the optimal strategies for the treatment of women with low-grade cervical abnormalities in populations of low sociocultural conditions and high risk of cervical cancer.

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