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Revista Colombiana de Cancerología
Print version ISSN 0123-9015
Abstract
YANEZ, Julian; DUQUE, Angélica and BELTRAN, María Isleña. Leiomyosarcoma ovarian cancer: a rare tumour with aggressive behaviour. rev.colomb.cancerol. [online]. 2017, vol.21, n.4, pp.230-235. ISSN 0123-9015. https://doi.org/10.10167j.rccan.2017.02.002.
Leiomyosarcomas may originate in most of the organs developed outside the central nervous system. There are documented cases of leiomyosarcomas of intestinal, mesenteric, ute rine, retroperitoneal, and of soft and vascular tissue origin. However, cases of primary ovarian leiomyosarcoma are extremely rare, with few cases reported in the international literature. Leiomyosarcomas are believed to be those that originate from the walls of existing vasculature in ovarian parenchyma, in the smooth muscle around the follicles, or from remnants of the Wolff duct. Most cases occur in post-menopausal patients, and have an unfavourable prognosis in the short term. The mainstay of treatment remains the complete tumour debulking, with negative surgical margins in order to reduce the potential for recurrence. The benefit of the use of adjuvant chemotherapy as part of treatment of this condition remains uncertain.
Keywords : Leiomyosarcoma; Myocytes; Ovarian.