Abstract

CASTILLO RAMIREZ, Alejandra; BURILLO LORENTE, José  and  MARCHENA YGLESIAS, Pablo Javier. Thrombotic microangiopathy in a patient with cancer of unknown origin. rev.colomb.cancerol. [online]. 2018, vol.22, n.2, pp.84-87. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2017.06.001.

Cancer-associated thrombotic microangiopathy (CATM) consists of microangiopathic haemolytic anaemia, thrombocytopenia, and ischaemic end organ-damage in patients with a known or unknown primary malignancy. Its diagnosis is challenging, as it is sometimes confused with thrombotic thrombocytopenic purpura, which is the most common cause of thrombotic microangiopathy in healthy patients. CATM can be a manifestation of the malignancy itself or a chemotherapy-related complication, with these patients having a poor prognosis. A case is presented of a patient who developed CATM in the context of metastatic cancer with an unknown primary site.

Keywords : Thrombocytopenia; Microangiopathic; Haemolytic Anaemia; Cancer With Unknown; Primary Site; Metastatic.

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