Abstract

PEREZ-SANCHEZ, Eduardo et al. Neuroendocrine rectal carcinoma: An infrequent tumor. rev.colomb.cancerol. [online]. 2018, vol.22, n.3, pp.126-129. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2017.09.002.

Neuroendocrine carcinoma (NC) is an infrequent pathology that is usually found in the advanced stages. The treatment is surgery, and combined chemotherapy andradiotherapy. A 73-year old woman was being studied for constitutional syndrome and rectal bleeding. After which, she was diagnosed with a poorly differentiated rectal NC, 5 cm from de anal margin with mesorectal lymph nodes. Induction chemotheraphy was started with partial response. A low anterior resection of rectum was performed with primary anastomoses and diverting loop ileostomy. The histology result was a large-cell NC, staged as pT2N0 Mx. She then received adjuvant chemotherapy. Rectal NC is infrequent, and usually presents between the fourth and seventh decade of life. Its symptoms are similar to colorectal adenocarcinoma, but it has a lower grade of differentiation, and is more aggressive. Neoadjuvant treatment is essential as it usually a metastatic disease at diagnosis, and helps to decrease the tumor size, and allows oncological surgery to be performed later.

Keywords : Neuroendocrine carcinoma; Drug therapy; Rectal tumors.

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