Abstract

MARTINEZ-MANZANO, Álvaro; BALSALOBRE-SALMERON, María Dolores  and  GARCIA-LOPEZ, María Aránzazu. Primary splenic diffuse large B-cell lymphoma double hit: A subtype of poor prognosis. rev.colomb.cancerol. [online]. 2018, vol.22, n.4, pp.143-145. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2018.08.002.

Diffuse Large-cell Lymphoma B (DLCLB) is the most common type of lymphoma, constituting 35% of all cases of Non-Hodgkin's Lymphoma (NHL). Primary Splenic Non-Hodgkin Lymphoma (PS-NHL) has an incidence of less than 1% of all lymphomas. The ''double hit'' lymphomas are related to the rearrangement of the MYC gene associated with another molecular alteration. They used to appear in older men and are mainly characterised by their aggressive behaviour.

Keywords : Non-Hodgkin Lymphoma; MYC gen; Double hit.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )