Abstract

CORONADO-ALEJANDRO, Edgar et al. Grey zone lymphoma with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma. Case report and literature review. rev.colomb.cancerol. [online]. 2018, vol.22, n.4, pp.146-150. ISSN 0123-9015.  https://doi.org/10.1016/j.rccan.2018.04.001.

In the grey zone lymphomas (GZL), there are overlapping characteristics between diffuse large B-cell lymphoma (DLBCL) and classic Hodgkin lymphoma (CHL). The unusual nature of the pathology combined with the heterogeneity of the disease, its recent description as a specific entity, its diagnostic difficulty, and the lack of sufficient therapeutic experience justifies its continuous description.

The case is presented of a patient with a fever of one month onset, with no response to initial management. A left inguinal lymph node biopsy reported a diagnosis of GZL with intermediate characteristics between DLBCL and CHL. Although there are no established guidelines for the management of this condition, the current evidence suggests a better response in treatments meant for diffuse large B-cell lymphoma. This same therapy was used in this patient, with a favourable clinical outcome.

Keywords : Grey Zone Lymphoma; Diffuse large B-cell lymphoma; Classical Hodgkin lymphoma; R-CHOP.

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