Abstract

MOLINA, Luisana; SALGADO, Juan  and  AMADO, Sandra. Pheochromocytoma and Paraganglioma: a Challenge beyond the Clinic. rev.colomb.cancerol. [online]. 2021, vol.25, n.1, pp.3-12.  Epub Aug 08, 2021. ISSN 0123-9015.  https://doi.org/10.35509/01239015.586.

Pheochromocytomas and Paragangliomas are rare tumors, originated from the chromaffin cells. They have a broad clinical spectrum from incidental finding to full clinical manifestations explain to overproduction of catecholamines. The biochemistry diagnosis is made by the measurement of free Metanephrines in plasma. Complete surgical removal is the optimal treatment, previously having a y 6 adrenergic receptors blockage. In case of metastasic disease, treatment options are palliative, limited and with a low rate response; the use of antiangiogenic treatments is under investigation.

Keywords : Pheochromocytoma; Paraganglioma; Surgery; Drug Therapy; Metanephrine.

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