Abstract

SANTANA, Diana; CALDERON, Pedro  and  CAICEDO, Lina. Primary malignant melanoma of the cervix: Case report. rev.colomb.cancerol. [online]. 2021, vol.25, n.1, pp.47-55.  Epub Aug 08, 2021. ISSN 0123-9015.  https://doi.org/10.35509/01239015.104.

Primary mucosal melanoma represents 1% of all cancers, the location in the cervix is rare, there are less than 100 cases reported in the literature to date, the data is limited in terms of staging and treatment, its prognosis is poor with survival rates of 10% at 5 years. We present a clinical case of a primary melanoma of the cervix in an 82-year-old patient with vaginal bleeding with evidence of a melanotic lesion in the cervix. The biopsy of the lesion reported poorly differentiated malignant tumor involvement, with an immuno-profile that favors melanoma. Extension studies were performed that did not show distant metastatic disease, the case was presented in a multidisciplinary oncological gynecology meeting, indicating treatment with exclusive external pelvic radiotherapy with palliative intention for symptom control taking into account patient comorbidities and ECOG functional status. (Eastern Cooperative Oncology Group) 3, after 10 months of follow-up the patient died.

Keywords : Cervix Uteri; Melanoma; Immunotherapy; Diagnosis; Uterine Hemorrhage; Immunohistochemistry.

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