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Revista Colombiana de Cancerología

Print version ISSN 0123-9015


OLIVEROS-WILCHES, Ricardo et al. Clinical practice guide for primary and secondary prevention and early diagnosis of gastric cancer. rev.colomb.cancerol. [online]. 2022, vol.26, n.1, pp.39-96.  Epub Sep 04, 2022. ISSN 0123-9015.


Generate recommendations for primary and secondary prevention, treatment of gastric preneoplastic lesions, and early diagnosis of gastric cancer in the adult population, to increase the detection of gastric cancer in early stages.

Material and methods:

The developer group was made up of health professionals, decision-makers, and a representative of the patients. Answerable clinical questions were constructed and outcomes were graded. The search for information in MEDLINE was carried out; EMBASE and CENTRAL, being updated on October 18, 2018. The search also covered other sources of information such as the Colombian Journal of Gastroenterology and the "snowball" reading of the references included. Experts in the field were contacted to identify studies. For the construction of the recommendations, a consensus was made according to the guidelines proposed by the GRADE methodology, weighing the benefits, the adverse effects derived from the intervention, the preferences of the patients, and the potential impact of the interventions on costs.


The short version of the "Clinical practice guidelines for the primary, secondary, and early diagnosis of gastric cancer" is presented together with its supporting evidence and respective recommendations.


As a central recommendation for implementation, it is recommended to eradicate H. pylori infection in patients with or without risk factors in whom it is detected to prevent gastric cancer precursor conditions. The Guide will need to be updated in three years.

Keywords : Clinical practice guide; gastric neoplasms; gastric cancer; primary prevention; secondary prevention.

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