Resumen

DIAZ, Miguel Ángel; SARRAZOLA, Dairo Mauricio  y  ORREGO, Julio César. Epidemiological, clinical and immunological characteristics of recurrent infection syndrome in individuals from low income neighborhoods from Cúcuta. Infect. [online]. 2008, vol.12, n.1, pp.28-37. ISSN 0123-9392.

Objective: To describe the clinical, epidemiological and immunological characteristics of the recurrent infection syndrome in children and adolescents living in four low incomes neighborhoods of Cúcuta. Methodology: We carried out a cross sectional survey from November 2003 to January 2004 in low incomes neighborhoods inhabited mostly by war refugees. We enrolled 328 subjects from 0 to 15 years of age who lived in four of those neighborhoods and their parents agreed to participate in the study. All the subjects fulfilled a standard questionnaire in order to classify then as a normal recurrent infection syndrome (NRIS) or suspicious of abnormal recurrent infection syndrome (ARIS). The second ones underwent a clinical examination and basic immune laboratory test to define the cause of ARIS. Results: The mean age was 6.1 years, one hundred sixty four were males (50.3%) and 49.7% women. Seventy (21.3%) of those was classified as (RIS) and 19 (5.8%) as cases suspicious of ARIS. Of the 19 suspicious cases, twelve were classified as non immunologic ARIS (ten cases for allergies and two for heart disease), five as immunologic ARIS with a possible case of selective deficiency of IgA and two reclassified as NRIS after the clinical and laboratory analysis. Discusion: In our study most of the cases of ARIS were caused by allergic diseases. The standard questionnaire was a useful tool to perform wide screening surveys in open population to detect cases suspicious of ARIS. We suggest that using the questionnaire accompanied by an appropriate clinical evaluation and basic laboratory tests allow finding out the cause of the ARIS in most of the cases.

Palabras clave : recurrent infection syndrome; war refugees; abnormal recurrent infection syndrome; nonimmunologic sira; immunologic sira; epidemiology.

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