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CURCI, Daniel; NACINOVICH, Francisco; MARTIN, Christin  and  TOSELLO, Claudia. Tygecicline for the treatment of Multiresistant Gram negative rods causing Mediastinitis: case reports and critic analysis. Infect. [online]. 2009, vol.13, n.1, pp.58-63. ISSN 0123-9392.

Mediastinitis is a life-threatening complication among patients undergoing cardiac surgery. Gram-positives cocci are the most frequent pathogens associated with post-surgical mediastinitis, being the Gram-negative etiology uncommon in most of the published series. We present our experience with four patients with mediastinitis due to multidrug-resistant Gram-negative bacilli, who have been treated with tigecycline.

Keywords : tigecicline; mediastinitis; Acinetobacter spp; Pseudomonas aeruginosa.

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