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Infectio
Print version ISSN 0123-9392
Abstract
CORTINA, Ana del Mar and TOBON, Alberto. Jaundice and hepatopathy in patients with malaria. Infect. [online]. 2010, vol.14, n.4, pp.277-285. ISSN 0123-9392.
Jaundice is a common finding in malaria patients. According to the World Health Organization, it is considered a sign of danger when accompanied by an important increase of bilirubin and it is frequently related to hepatic dysfunction and injury to other organs. Liver injury in these patients is common and it is associated with other complications. If it is identified and treated early, it is reversible. This paper reviews the semiological value of jaundice as an indicator of complicated malaria; it explains its pathogenesis and the mechanisms of liver damage. It also focuses on the patient with hepathopathy, distinguishing hepatic dysfunction, hepatic failure and hepatic encephalopathy.
Keywords : Jaundice; complicated malaria; hepathopathy; hepatic dysfunction; hepatic failure.