Abstract

CORTES, Jorge Alberto et al. Consensus for antimicrobial use in critically ill patients with renal failure or at risk of suffering it. Infect. [online]. 2011, vol.15, n.1, pp.49-63. ISSN 0123-9392.

A growing number of critically ill patients are being taken care with sepsis secondary to bacterial or mycotic infections. In this group of patients, sepsis per se is a risk factor for the development of renal failure, which has been related to an increased risk of hospital mortality. An expert panel in infectious diseases, critical care and renal diseases prepared an evidence based consensus over the use of antimicrobials (antibacterial and antifungal agents) in critically ill patients with renal failure or at risk of suffering it. A sytematic review of the scientific literature was performed and recommendations were established by means of a consensus using the Delphi method. Recommendations proposed by this consensus are intended to be use by healthcare workers who are in charge of this kind of patients with the aim to identify the group of patients with higher risk of developing renal failure and to establish the therapeutic measures theat have the best outcome and lower frequenc of severe side effects in renal function. An implementation strategy was added with the recommendations.

Keywords : Antibacterial agents; antifungal agents; acute renal failure; acute renal injury; consensus; drug toxicity.

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