SciELO - Scientific Electronic Library Online

vol.15 issue2Validation of anti-Toxoplasma IgM ELISA tests in newborn screening programsRole of chlorhexidine in the prevention of health care related infections author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google



Print version ISSN 0123-9392


CASTRO-JIMENEZ, Miguel Ángel et al. Diagnosis of fungal opportunistic infections in HIV/AIDS patients: A cases study in Colombia. Infect. [online]. 2011, vol.15, n.2, pp.92-97. ISSN 0123-9392.

Objectives: To identify the opportunistic fungal infections affecting patients with HIV/AIDS, to determine their demographic and socioeconomic characteristics and the number of CD4+ T cells. Materials and methods: This is a descriptive case series study based on a major study aimed at determining the type and frequency of opportunistic diseases in HIV/AIDS patients. A case was defined as an HIV/AIDS patient who had evidence of fungal infection at baseline. Eligible patients were being treated at two clinical institutions located in Bogotá, Colombia, between October 2007 and May 2010. Respiratory, cerebrospinal fluid and blood samples and scrapping/swabs of oral lesions were collected in order to determine the presence of Histoplasma capsulatum, Paracoccidioides brasiliensis, Cryptococcus neoformans or Candida spp. Proportions were used for qualitative variables and medians for quantitative variables. Results: Overall, 33 (10,2%) patients were diagnosed as having one or more of the evaluated fungal infections , out of 336. Seventy five per cent of them were between the ages of 23 and 42. The frequencies of these fungal infections were: H. capsulatum (n=1; 3.0%), P. brasiliensis (n=1; 3.0%), C. neoformans (n=25; 75.8%), and Candida spp. (n=7; 21.2%). The median values of CD4+ T cells were 176 or less, independently of clinical manifestations. Conclusion: Further studies are required to identify factors contributing to the presence of fungal opportunistic infections in these patients.

Keywords : Case studies; acquired immunodeficiency syndrome; mycoses; cryptococcosis; histoplasmosis; candidiasis; paracoccidioidomycosis; Colombia.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License