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RODRIGUEZ, Diego Andrés; BUSTACARA, Maximiliano; PINILLA, Adriana Patricia  and  HENAO, Liliana. Choledocholithiasis and cholangitis as a complication of ceftriaxone in children: a case report. Infect. [online]. 2012, vol.16, n.3, pp.187-190. ISSN 0123-9392.

Ceftriaxone is widely used in children because it has a great spectrum, long half-life and good penetration. Is generally well tolerated, although in children who receive the drug, it often presented pseudocolelitiasis and biliary sludge. This is favored because about 40% of the drug is eliminated unchanged in bile where it behaves as an anion with high affinity for calcium salts. Most cases present as asymptomatic or minimally symptomatic and spontaneous resolution, only when the drug is no longer taken. A case of a 4 year old girl who received ceftriaxone for 14 days for sinusitis and on day 5 develops gall bladder stones that grow to 11 mm and last 55 days to go away, the day 34 presents cholecystitis, cholangitis and choledocholithiasis requiring medical management to resolution.

Keywords : Ceftriaxone; Cholelithiasis; Child.

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