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BONILLA, Diego Andrés; CUERVO, Sonia Isabel  and  GOMEZ, Julio César. Usefulness of procalcitonin in the management of adult patients with hematological malignancies with fever and chemotherapy-induced neutropenia: State of the art. Infect. [online]. 2012, vol.16, n.4, pp.223-229. ISSN 0123-9392.

Procalcitonin has proven useful to rule out meningitis in febrile children with unknown source of infection, and in the monitoring of patients with severe community-acquired pneumonia and health care-associated pneumonia including those with ventilator-associated pneumonia to guide antimicrobial therapy. In patients with fever and chemotherapy-induced neutropenia, procalcitonin has been studied to predict bacterial blood-stream infections and poor outcomes, with variable results in part because heterogeneous population included in those studies. Our aim is to describe the utility of procalcitonin in the management of adult patients with hematological malignancies and chemotherapy-induced febrile neutropenia.

Keywords : Procalcitonin; Fever; Febrile neutropenia; Chemotherapy-induced neutropenia; Leukemia; Hematological Malignancies.

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