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Infectio

Print version ISSN 0123-9392

Abstract

CIFUENTES C, Yolanda  and  VALLEJO R, Cristian. Anicteric Hepatitis as Congenital Syphilis Manifestation. Infect. [online]. 2013, vol.17, n.3, pp.163-166. ISSN 0123-9392.

Congenital syphilis is a global public health problem. The majority of infected children have no clinical manifestations of the disease and the specific IgM determination in newborns has low diagnostic performance. The diagnosis depends mostly of the diagnosis in mothers before birth. We report a newborn that was inadequately treated prenatally. At birth, the liver involvement was detected, with increase in aspartate amino transferase and of conjugated fractions of bilirubin. CNS involvement was ruled out and cultures of blood and urine were negative for bacteria. Determinations for IgM of CMV, rubella, toxoplasmosis and herpes I and II, were negative. Transfontanellar, heart, kidney, urinary tract and hepatobiliary ultrasound examinations were normal. Crystalline penicillin treatment for 14 days was undertaken, obtaining normal levels of bilirubin and aspartate aminotransferase at the end of treatment. The clinical and serological follow-up after 3 months showed a normal growth and development pattern with non-reactive VDRL tests.

Keywords : Syphilis; Congenital; Hepatitis; Hyperbilirubinemia Conjugated.

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