Abstract

MARTINEZ BUITRAGO, Ernesto et al. Frequency and antibiotics resistance profi les of microbiological isolates at 13 clinics and referral hospitals in Santiago de Cali - Colombia. Infect. [online]. 2014, vol.18, n.1, pp.3-11. ISSN 0123-9392.

Background: Bacterial resistance has established itself as a threat to healthcare systems in the management of infectious diseases. Epidemiological surveillance of bacterial resistance has proven to be an effective strategy to examine the patterns of antimicrobial susceptibility in order to develop regional containment strategies and to manage the appropriate use of antibiotics. Objective: To describe the microbiological profiles of isolates and the antimicrobial resistance of major gram-negative and gram-positive bacteria in clinics and hospitals of Santiago de Cali, Colombia. Methods: Descriptive study framed by the epidemiological surveillance strategy of the bacterial resistance developed between the years 2010 to 2012 in 13 institutions of higher complexity. Files were collected monthly in WHONET format and were tested for data quality. The analysis was stratified by type of hospital location, in addition to a trend analysis over the 3-year follow-up period. Results: A total of 65% of the isolates were of the Enterobacteriaceae family and 11.4% were Staphylococcus spp . Escherichia coli showed up to 17% resistance to 3rd generation cephalosporins, while Klebsiella pneumoniae increased its carbapenem resistance profile to 2.7% in the ICU. Pseudomonas aeruginosa presented a multidrug resistant (MDR) profile of up to 21% in ICU and in the general ward. Conclusions: There is a high prevalence of antimicrobial resistance in the region; we must strengthen strategies for surveillance, prevention and control of bacterial resistance in hospital settings and in the community .

Keywords : Epidemiological surveillance; Bacterial drug resistance; Colombia.

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