Abstract

ZAPATA, Andrés et al. Lymphoid interstitial pneumonitis in children infected with type 1 human immunodefi ciency virus from areas with high pulmonary tuberculosis prevalence. Infect. [online]. 2014, vol.18, n.1, pp.22-27. ISSN 0123-9392.

Background: Little is known about Lymphoid Interstitial Pneumonitis (LIP) in children with HIV infection. Aims: To describe the clinical and pathological characteristics of LIP in infected children in a referral center for pediatric HIV in Cali (Colombia). Methods: Case series based on retrospective analysis of clinical charts among HIV-infected children with chronic lung disease and lung-biopsy proven LIP between the years 2001 and 2012. Results and conclusions: 10 of 12 cases of LIP were confirmed by lung biopsy. Significant clinical and respiratory functional improvement was obtained in all cases after prednisone therapy, excepting one child who presented persistent cough. No case of pulmonary TB was detected in our cohort. Lung biopsy was critical to obtain an accurate diagnosis.

Keywords : Lymphoid Interstitial Pneumonitis; Human Immunodeficiency Virus; Children; Pulmonary Tuberculosis; Chronic Lung Disease.

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