Abstract

TORO-LEZCANO, Mónica M. et al. Invasive Aspergilosis in ICU . Infect. [online]. 2015, vol.19, n.1, pp.35-39. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2014.05.006.

Invasive aspergilosis (IA) is caused by Aspergillum particles inhalation such as mildew and yeast. They live in the soil as a natural habitat. This infection has been described in patients with a bone marrow transplant and serious neutropenia (<500mm 3 ). Inward patients of intensive care unit (ICU) can be also susceptible to them, and even more with risk factors associated such as chronic obstructive pulmonary disease (COPD), liver cirrhosis, autoimmune diseases with inmunosupressor therapy and solid organ transplantation, where mortality can reach 80% of cases. A case of IA in a man of 56 years old is described. He had smoking history without previous spirometric assessment. The patient developed IA during stay at the intensive care unit. Aspergillus septate hiphae were observed in the biopsy at the carina's ulcer. Galactomannan assay was positive in bronchioalvelar fluid. The patient had good clinical response to treatment with Voriconazole.

Keywords : Invasive aspergillosis; Chronic obstructive pulmonary disease; Galactomannan.

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