Abstract

AGUDELO-GONZALEZ, Stefany; MURCIA-SANCHEZ, Felix; SALINAS, Diego  and  OSORIO, Johanna. Opportunistic infections in patients with HIV in Neiva´s University Hospital, Colombia.2007-2012 . Infect. [online]. 2015, vol.19, n.2, pp.52-59. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2014.11.008.

Introduction: Since the beginning of the HIV pandemic, opportunistic infections (OI) have determined the prognosis. Access to antiretroviral therapy (HAART) led to significant changes in the natural history of the disease. Objective: To describe the clinical characteristics of patients with HIV and OIs admitted to the Universitary Hospital of Neiva (HUHMP). Materials and methods: An observational, descriptive, retrospective study of hospitalized adults with HIV/AIDS admitted due to OIs during 2007-2012; pregnant women were excluded. The data were processed using Epi info7. Results: A total of 286 patients met the selection criteria. The mean age was 38.6 years and 72.7% were men. 76.5% were diagnosed with HIV prior to entry, 45.6% were not receiving HAART.On admission 39% of patients had leukopenia, 15% renal failure, 70% CD4 + lymphocyte counts< 200 cells/mm ³ and 64% viremia > 100,000 copies/mm ³ . The most common discharge diagnoseswere cerebral toxoplasmosis (52%), mucocutaneous candidiasis (35%) and tuberculosis (31%). Hospital mortality was 13%. Conclusion: Despite improvement in the management of HIV/AIDS in the southwestern region of Colombia, most HIV patients are hospitalized at advanced HIV-stages due to OIs, and are not receiving HAART. The most common OI was cerebral toxoplasmosis.

Keywords : Opportunistic infection; HIV related; AIDS.

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